ABSTRACT
Acquired Blaschkoid dermatitis characterised by unilateral relapsing inflammatory disease along the lines of Blaschko. A 40-year-old Indian male presented with unilateral erythematous, itchy grouped papules on the left side of the chest, abdomen, back and left arm of 15 days duration. The eruption stopped abruptly at the midline of the torso, completely sparing the right side of the body. The lesions were arranged in whorls and streaks corresponding to the lines of Blaschko. Skin biopsy showed hyperkeratosis and features suggestive of sub-acute spongiotic dermatitis with lymphocytic infiltrate around the blood vessels in the dermis. Patient was diagnosed as a case of Blaschkoid dermatitis. To the best of our knowledge, this is the first case of this condition being reported from India.
Subject(s)
Adult , Biopsy , Cyproheptadine/therapeutic use , Dermatitis/drug therapy , Dermatologic Agents/therapeutic use , Glucocorticoids/therapeutic use , Histamine H1 Antagonists/therapeutic use , Humans , Hydrocortisone/analogs & derivatives , Keratosis/pathology , Lymphocytes/pathology , Male , Prednisolone/therapeutic use , Skin/pathology , Skin Diseases, Papulosquamous/drug therapyABSTRACT
Two cases of Ehlers-Danlos syndrome affecting two real brothers are being reported. Both of them presented with features of atrophy and hyperextensibility of skin, hypermobility of joints and scarring at the sites of trauma. The elder brother also had kyphoscoliosis and hypogonadism with testicular failure.
Subject(s)
Adolescent , Ehlers-Danlos Syndrome/diagnosis , Follow-Up Studies , Genetic Predisposition to Disease , Hand Deformities, Congenital/diagnosis , Humans , Hypogonadism/diagnosis , Kyphosis/diagnosis , Male , Risk Assessment , Severity of Illness Index , SiblingsABSTRACT
Cicatricial pemphigoid (CP) occurring in a 60-year-old male is described. He had involvement of conjunctival, nasal and oral mucosae, in addition to skin lesions. Diagnosis was confirmed by histopathology. He responded well to oral steroids and dapsone. However, vision in one eye was lost.